Activation of Parkin by a Molecular Glue
Time: 2:00 pm
day: Conference Day One
Details:
- Discovery of the THPP compound series of Parkin activators
- Deconvolution of the mechanism of action of the Parkin activator as a molecular glue
- Broader implications of understanding this binding site and the considerations for designing other ring-between-ring E3 ligase molecular glues
