Activation of Parkin by a Molecular Glue

Time: 2:00 pm
day: Conference Day One

Details:

  • Discovery of the THPP compound series of Parkin activators
  • Deconvolution of the mechanism of action of the Parkin activator as a molecular glue
  • Broader implications of understanding this binding site and the considerations for designing other ring-between-ring E3 ligase molecular glues

Speakers: