Round Table Discussion: Cross-Disciplinary Perspectives on PK/PD in Protein Degradation Drug Development for Neurodegenerative Diseases
Time: 12:00 pm
day: Conference Day One
Details:
Current Challenges and Opportunities in PKPD for Neurodegenerative Diseases:
- What are the unique challenges in developing PKPD models for neurodegenerative diseases?
- How can we leverage existing PKPD frameworks to better understand the efficacy and safety of protein degraders?
Mechanistic Insights and Translational Approaches:
- How do the mechanisms of action of protein degraders differ from traditional small molecules in terms of PKPD?
- What translational strategies can be employed to predict clinical outcomes from preclinical data
Innovative Technologies and Methodologies:
- What are the latest technological advancements in PKPD modeling for protein degraders?
- How can computational techniques and high-throughput screening be integrated into PKPD studies?