Targeting Protein Degradation in Parkinson’s: a preclinical perspective
Time: 2:00 pm
day: Conference Day One
Details:
- Therapeutic Landscape and Future Directions – Reviewing current and emerging drug development strategies targeting protein degradation in Parkinson’s.
- Pathological vs. Non-Pathological Proteins – Addressing tactics for targeting synuclein protein aggregation vs degradation of proteins that drive synuclein pathology
- Animal Models for Enhancing Protein Degradation – Overview of rodent and non-human primate models used in preclinical research
- Autophagy Activation as a Potential Therapeutic Strategy – Examining the effects of an exemplar molecule that promote protein degradation via autophagy in rodent and non human promote models of Parkinson’s treatment