Mikolaj Slabicki
Company: The Broad Institute of MIT & Harvard
Job title: Assistant Professor of Medicine, Harvard Medical School
Seminars:
Round Table Discussion: Approaches to degrade proteins with molecular glues, and their therapeutic role 3:45 pm
Novel studies in degrading pathogenic proteins by recruiting them to E3 ubiquitin ligases via small molecules that remodel protein surfaces to induce non-endogenous E3–substrate interactions Functional genomics, structural, and computational studies to identify how a small molecule degrades a B-cell lymphoma target by polymerizing it Polymerization potential of other transcription factors and how it opens…Read more
day: Conference Day Two
WORKSHOP D
STRATEGIES OF SUCCESSFUL PROTEIN DEGRADATION FOR BETTER UNDERSTANDING AND FUTURE PROGRESSION 1:30 pm - 4:30 pm
STRATEGIES OF SUCCESSFUL PROTEIN DEGRADATION FOR BETTER UNDERSTANDING AND FUTURE PROGRESSION
Examining studies of previously developed protein degraders is vital for advancing current and novel approaches by understanding the methods that have proven successful in order to advance drug development Workshop highlights include: Investigating studies on protein degraders to deepen the understanding of methodologies known to be successful for advancing more drugs to clinic Exploring the…Read more
day: Workshop D