Pranam Chatterjee
Company: Duke University
Job title: Assistant Professor of Biomedical Engineering & Co-Founder (UbiquitX)
Seminars:
WORKSHOP C
INTRODUCTION TO PROTEIN DEGRADER BIOLOGY TO ENHANCE INSIGHTS FOR GREATER CONTEXT & COLLABORATION 9:30 am - 11:30 am
INTRODUCTION TO PROTEIN DEGRADER BIOLOGY TO ENHANCE INSIGHTS FOR GREATER CONTEXT & COLLABORATION
Neuroscience experts have begun exploring the use of protein degradation as a drug development approach, requiring better understanding of the specialised mechanisms that can be utilised in combating CNS diseases Join this workshop to: Understand the latest research on protein synthesis and the folding and mis-folding of proteins to get to grips with the fundamentals…Read more
day: Workshop C
Programmable Modulators of Undruggable Targets via Generative Language Models 9:30 am
Generative language models can design selective peptide binders to any target, including those that are disordered and lack binding pockets Peptide binders can be fused to E3 ubiquitin ligases or deubiquitinases, driving programmable target degradation of proteins such as GFAP and mHTT and stabilization of proteins, such as p53 These peptide-enzyme fusions can be readily…Read more
day: Conference Day Two