Simon Glerup

Company: Draupnir Bio

Job title: Chief Scientific Officer

Seminars:

Showcasing Development of Degraders to Target Extracellular Pathological Proteins Via Lysosomal Degradation 1:30 pm

Targeting extracellular proteins and introduction to degradation technology Designing degraders inducing lysosomal-mediated degradation for CNS applications Showcasing preclinical data of degrader mechanism of actionRead more

day: Conference Day One

Panel Discussion: Striving Beyond Proteasome Capacity: Debating the Different Strategies for Protein Degradation in CNS 11:30 am

Outlining the theoretical biological limitations of proteasome-mediated degradation – does this correlate with reported PROTAC capabilities? Understanding the potential of lysosome and autophagy-mediated degradation to target extracellular, aggregated CNS disease proteins Weighing up strategies of preventing new aggregates forming against degrader existing disease proteins – which is the best route to go?Read more

day: Conference Day One