Yong-Tae Kwon

Company: AUTOTAC Bio

Job title: Chief Executive Officer

Seminars:

Panel Discussion: Striving Beyond Proteasome Capacity: Debating the Different Strategies for Protein Degradation in CNS 11:30 am

Outlining the theoretical biological limitations of proteasome-mediated degradation – does this correlate with reported PROTAC capabilities? Understanding the potential of lysosome and autophagy-mediated degradation to target extracellular, aggregated CNS disease proteins Weighing up strategies of preventing new aggregates forming against degrader existing disease proteins – which is the best route to go?Read more

day: Conference Day One

Showcasing Preclinical Proof of Concept of Autophagy-Mediated Protein Degradation Against Aggregated Targets in the Brain 10:00 am

Evaluating AUTOTAC engagement and efficacy in targeted CNS protein degradation Detailing AUTOTAC design to ensure controlled autophagy degradation via P62 targeting Explaining experimental set-up and model systems utilized for testing AUTOTAC therapiesRead more

day: Conference Day One