Panel Discussion: Striving Beyond Proteasome Capacity: Debating the Different Strategies for Protein Degradation in CNS
Time: 11:30 am
day: Conference Day One
Details:
- Outlining the theoretical biological limitations of proteasome-mediated degradation – does this correlate with reported PROTAC capabilities?
- Understanding the potential of lysosome and autophagy-mediated degradation to target extracellular, aggregated CNS disease proteins
- Weighing up strategies of preventing new aggregates forming against degrader existing disease proteins – which is the best route to go?
